Vitamin AD3E Injection: veterinary dose and monograph

At a glance

Drug class

Veterinary drug

Also known as

Intavita, Vimeral injection, AD3E Vet

Species with doses

Cattle, Horses, Goats, Sheep, Pigs and Buffalo

Routes

IM

Last reviewed

1 October 2026

Indications

• Vit A / D / E deficiency prevention in stall-fed / dry-paddock cattle
• Post-parturient calcium / vitamin metabolism support (alongside calcium)
• Reproductive support — post-AI luteal function adjunct
• Recovery from scours, deworming, or chronic disease
• Pre-monsoon prophylaxis in heavily-stocked feedlots

Vitamin AD3E Injection dose by species

Doses are per administration unless stated. mg/kg doses scale with body weight; per-animal, per-quarter and infusion-rate doses are shown as the reference writes them.

Cattle

• Prophylactic AD3E supplementation: Intavita catalogue: 5 mL per 300 kg deep IM. Repeat every 30–60 days. Vimeral syrup PO 50–100 mL daily for 10–14 days as alternative.

Horses

• Adult horse — prophylaxis: Catalogue: 5 mL per adult horse IM.

Goats

• Adult goat — prophylaxis: Catalogue: 1–2 mL per adult goat IM.

Sheep

• Adult sheep — prophylaxis: Catalogue: 1–2 mL per adult sheep IM.

Pigs

• Adult pig — prophylaxis: Catalogue: 2–5 mL per adult pig IM.

Buffalo

• Prophylactic AD3E supplementation / fertility support: Intavita/Vimeral labels buffalo with cattle: 5 mL per 300 kg deep IM q30–60 d, or Vimeral syrup 50–100 mL PO daily ×10–14 d. Used in buffalo for peri-partum support and to correct anoestrus linked to vitamin A/E deficiency.

Contraindications

Hypervitaminosis A or D (rare in practice). Severe hepatic / renal disease (caution). DO NOT re-inject within 30 days — risk of hypervitaminosis A.

Species-specific warnings

Cattle: Deep IM neck only. Do not re-inject within 30 days. Useful pre-monsoon prophylaxis.

Adverse effects

• Injection-site reaction (transient swelling)
• Hypervitaminosis A on over-dosing (skeletal changes, dermatitis)

Pregnancy and lactation

Safe during pregnancy at recommended doses — actually beneficial peri-partum.

Monitoring

• Spacing between injections — do not re-inject within 30 days
• Body condition / coat appearance
• Clinical response in reproductive / scours cases

Clinical pearls

• Mid-lactation high-producing dairy cow with dull coat: 5 mL Intavita IM + multimineral bolus often restores body condition over 4–6 weeks
• Post-deworming recovery: pair AD3E injection with iron + B12 to accelerate recovery
• Reproductive support — 5 mL IM at the time of breeding has been used in repeat-breeder cows in field practice
• Vimeral oral syrup is a calf-friendly alternative when IM is logistically difficult

Mechanism of action

Vit A (retinol) — epithelial integrity, vision, reproduction; Vit D3 (cholecalciferol) — calcium and phosphorus homeostasis via 1,25-OH vit D activation; Vit E (alpha-tocopherol) — antioxidant, membrane stabilisation, muscle function. Biotin — keratinisation of hoof, skin, hair. Depot oil-based injection releases over 30–60 days.

Formulations and products

• Intavita 5 mL ampoule — Vit A 1.25 M IU + D3 125 K IU + E 500 IU + Biotin 62.5 mcg per 5 mL (Intas)
• Intavita Injection (Intas (Neovet)) — Vit A 250 000 IU + D3 25 000 IU + E 100 IU + Biotin 12.5 µg per mL, Oil-based depot IM injection
• Vimeral Syrup (Virbac India) — Vit A + D3 + E + B12 oral syrup, Oral syrup
• Surevet-AD3 (Assure Biotech, Jagadhri (HR)) — Vitamin A 250000 IU + Vitamin D3 25000 IU + Vitamin E 100 IU + Biotin 12.5 mcg per mL, Oily injection (sesame oil base) - IM

Storage

15–25 °C, protect from light.

Before you use this dose

Reference doses for veterinary professionals. Confirm the dose against the product label, the patient’s condition, current guidance and local regulations before use; the attending veterinarian remains responsible for every clinical decision.

Other hormones, emergency drugs, supplements and other drugs

• Tranexamic Acid
• Trilostane
• Vinblastine
• Vincristine
• Vitamin E / Selenium
• Yohimbine
• Zonisamide

Frequently asked questions